分子生物遺伝学研究領域 片山研究室

原著(英文)

  1. Kiya K, Kubo T, Kawai K, Matsuzaki S, Muramatsu R, Maeda D, Fujiwara T, Nishibayashi A, Kanazawa S, Yano K, Amano G, Katayama T, Hosokawa K.
    Endothelial cell-derived endothelin-1 is involved in abnormal scar formation by dermal fibroblasts through RhoA/Rho-kinase pathway.
    Exp Dermatol. Nov 28. doi: 10.1111/exd.13264. [Epub ahead of print] (2016)
  2. Yoshimura T*+, Hayashi A*, Handa-Narumi M, Yagi H, Ohno N, Koike T, Yamaguchi Y, Uchimura K, Kadomatsu K, Sedzik J, Kitamura K, Kato K, Trapp BD, Baba H, Ikenaka K+.(*Equal Contribution; +Corresponding Author)
    GlcNAc6ST-1 regulates sulfation of N-glycans and myelination in the peripheral nervous system.
    Sci Rep. in press (2017)
  3. Yoshimura T*, Stevens SR*, Leterrier C, Stankewich MC, Rasband MN. (*Equal Contribution)
    Developmental changes in expression of betaIV spectrin splice variants at axon initial segments and nodes of Ranvier.
    Front Cell Neurosci. in press .(2017)
  4. Sugio S, Tohyama K, Oku S, Fujiyoshi K, Yoshimura T, Hikishima K, Yano R, Fukuda T, Nakamura M, Okano H, Watanabe M, Fukata M, Ikenaka K, Tanaka FK.
    Astrocyte-mediated infantile-onset leukoencephalopathy mouse model.
    Glia 65, 93-105, (2017).
  5. Fujioka T, Inohara K, Okamoto Y, Masuya Y, Ishitobi M, Saito DN, Jung M, Arai S, Matsumura Y, Fujisawa TX, Narita K, Suzuki K, Tsuchiya KJ, Mori N, Katayama T, Sato M, Munesue T, Okazawa H, Tomoda A, Wada Y, Kosaka H.
    Gazefinder as a clinical supplementary tool for discriminating between autism spectrum disorder and typical development in male adolescents and adults.
    Mol Autism.  7:19. doi: 10.1186/s13229-016-0083-y. eCollection 2016.
  6. Miyata S, Taniguchi M, Koyama Y, Shimizu S, Tanaka T, Yasuno F, Yamamoto A, Iida H, Kudo T, Katayama T, Tohyama M. 
    Association between chronic stress-induced structural abnormalities in Ranvier nodes and reduced oligodendrocyte activity in major depression.
    Sci Rep.  6:23084. doi: 10.1038/srep23084.2016
  7. Matsuzaki S, Lee L, Knock E, Srikumar T, Sakurai M, Hazrati LN, Katayama T, Staniszewski A, Raught B, Arancio O, Fraser PE.
    SUMO1 Affects Synaptic Function, Spine Density and Memory.
    Sci Rep.  5:10730. doi: 10.1038/srep10730, 2015
  8. Miyatake Y, Matsuzaki S, Taniguchi M, Takamura H, Yamada K, Hattori T, Kameyama T, Manabe T*, Tohyama M, Katayama T*.
    Identification and characterization of a novel splice variant of disrupted in schizophrenia 1 (Disc1).
    J Brain Sci.. 45, 5-34, 2015
  9. Matsuzaki S, Hiratsuka T, Kubo T, Katayama T.
    Physiological ER stress mediates the differentiation of fibroblasts
    PLoS ONE Apr 30;10(4):e0123578. doi: 10.1371, 2015
  10. Shibasaki Y, Hayata-Takano A, Hazama K, Nakazawa T, Shintani N, Kasai A, Nagayasu K, Hashimoto R, Tanida M, Katayama T, Matsuzaki S, Yamada K, Taniike M, Onaka Y, Ago Y, Waschek JA, Köves K, Reglődi D, Tamas A, Matsuda T, Baba A, Hashimoto H.
    Atomoxetine reverses locomotor hyperactivity, impaired novel object recognition, and prepulse inhibition impairment in mice lacking pituitary adenylate cyclase-activating polypeptide.
    Neuroscience 297:95-104, 2015
  11. Okamoto M, Iguchi T, Hattori T, Matsuzaki S, Koyama Y, Taniguchi M, Komada M, Xie MJ, Yagi H, Shimizu S, Konishi Y, Omi M, Yoshimi T, Tachibana T, Fujieda S, Katayama T, Ito A, Hirotsune S, Tohyama M, Sato M.
    DBZ Regulates Cortical Cell Positioning and Neurite Development by Sustaining the Anterograde Transport of Lis1 and DISC1 through Control of Ndel1 Dual-Phosphorylation.
    J Neurosci. 18;35(7):2942-58, 2015
  12. Shintani N, Onaka Y, Hashimoto R, Takamura H, Nagata T, Umeda-Yano S, Mouri A, Mamiya T, Haba R, Matsuzaki S, Katayama T, Yamamori H, Nakazawa T, Nagayasu K, Ago Y, Yagasaki Y, Nabeshima T, Takeda M, Hashimoto H.
    Behavioral characterization of mice overexpressing human dysbindin-1.
    Mol Brain. 7(1):74. 2014. [Epub ahead of print]
  13. Miyoshi K, Kasahara K, Murakami S, Takeshima M, Kumamoto N, Sato A, Miyazaki I, Matsuzaki S, Sasaoka T, Katayama T, Asanuma M.
    Lack of dopaminergic inputs elongates the primary cilia of striatal neurons.
    PLoS ONE. , 9(5):e97918, 2014
  14. Iwata K, Matsuzaki H, Tachibana T, Ohno K, Yoshimura S, Takamura H, Yamada K, Matsuzaki S, Nakamura K, Tsuchiya KJ, Matsumoto K, Tsujii M, Sugiyama T, Katayama T, Mori N
    N-ethylmaleimide-sensitive factor interacts with the serotonin transporter and modulates its trafficking: implications for pathophysiology in autism.
    Mol Autism. 5:33. doi: 10.1186/2040-2392-5-33. 2014. (co-corresponding author)
  15. Hattori T, Shimizu S, Koyama Y, Emoto H, Matsumoto Y, Kumamoto N, Yamada K, Takamura H, Matsuzaki S, Katayama T, Tohyama M, Ito A.
    DISC1 (Disrupted-in-Schizophrenia-1) Regulates Differentiation of Oligodendrocytes
    PLoS ONE, 9(2):e88506, 2014
  16. Shimizu S, Koyama Y, Hattori T, Tachibana T, Yoshimi T, Emoto H, Matsumoto Y, Miyata S, Katayama T, Ito A, Tohyama T.
    DBZ, a CNS-specific DISC1 binding protein, positively regulates oligodendrocyte differentiation.
    Glia 62(5):709-24, 2014
  17. Morihara T, Hayashi N, Yokokoji M, Akatsu H, Silverman MA, Kimura N, Sato M, Saito Y, Suzuki T, Yanagida K, Kodama TS, Tanaka T, Okochi M, Tagami S, Kazui H, Takashi Kudo T, Hashimoto R, Itoh N, Nishitomi K, Kabata-Yamagichi Y, Tsunoda T, Takamura H, Katayama T, Kimura R, Kaminoa K, Hashizume Y, Takeda M.
    Transcriptome analysis of distinct mouse strains reveals kinesin light chain-1 splicing as an amyloid beta accumulation modifier.
    PNAS 111(7):2638-43., 2014
  18. Magome T, Hattori T, Taniguchi M, Ishikawa T, Miyata S, Yamada K, Takamura H, Matsuzaki S, Ito A, Tohyama M, Katayama T.
    XLMR protein related to neurite extension (Xpn/KIAA2022) regulates cell-cell and cell-matrix adhesion and migration.
    Neurochem Int. 63(6):561-569., 2013
  19. Miyata S, Mizuno T, Koyama Y, Katayama T, Tohyama M.
    The endoplasmic reticulum-resident chaperone heat shock protein 47 protects the Golgi apparatus from the effects of o-glycosylation inhibition.
    PLoS ONE. 8(7):e69732., 2013
  20. Koyama Y, Hattori T, Shimizu S, Taniguchi M, Yamada K, Takamura H, Kumamoto N, Matsuzaki S, Ito A, Katayama T, Tohyama M.
    DBZ (DISC1-binding zinc finger protein)-deficient mice display abnormalities in basket cells in the somatosensory cortices.
    J Chem Neuroanat. S0891-0618(13)00062-8., 2013
  21. Takamura H, Koyama Y, Matsuzaki S, Yamada K, Hattori T, Miyata S, Takemoto ., Tohyama M, Katayama T. 
    TRAP1 controls mitochondrial fusion/fission balance through Drp1 and Mff expression.
    PLoS ONE, 7(12):e51912 , 2012
  22. Ishikawa T, Miyata S, Koyama Y, Yoshikawa K, Hattori T, Kumamoto N, Shingaki K, Katayama T, Tohyama M
    Transient expression of Xpn, an XLMR protein related to neurite extension, during brain development and participation in neurite outgrowth
    Neuroscience, 214:181-91, 2012
  23. Thanseem I, Anitha A, Nakamura K, Suda S, Iwata K, Matsuzaki H, Ohtsubo M, Ueki T, Katayama T, Iwata Y, Suzuki K, Minoshima S, Mori N.
    Elevated Transcription Factor Sp1 in Autistic Brains Alters the Expression of Autism Candidate Genes.
    Biological Psychiatr , 71(5):410-8 , 2012
  24. Miyata S, Koyama Y, Takemoto K, Yoshikawa K, Ishikawa T, Taniguchi M, Inoue K, Aoki M, Hori O, Katayama T, Tohyama M.
    Plasma Corticosterone Activates SGK1 and Induces Morphological Changes in Oligodendrocytes in Corpus Callosum
    PLoS ONE 6(5): e19859, 2011
  25. Takemoto K, Miyata S, Takamura N, Katayama T, Tohyama M.
    Mitochondrial TRAP1 regulates the unfolded protein response in the endoplasmic reticulum.
    Neurochem Int 58(8):880-7, 2011
  26. Hiratsuka T, Matsuzaki S, Miyata S, Kinoshita M, Kakehi K, Nishida S, Katayama T, Tohyama M.
    Yokukansan inhibits neuronal death during ER stress by regulating the unfolded protein response
    PLoS ONE 5(10):e13280, 2010
  27. Koyama Y, Hiratsuka T, Matsuzaki S, Yamagishi S, Kato S, Katayama T*, Tohyama M.
    Familiar Amyotrophic Lateral Sclerosis (FALS)-linked SOD1 Mutation Accelerates Neuronal Cell Death by Activating Cleavage of Caspase-4 under ER Stress in an in vitro Model of FALS
    Neurochem Int, 57(7):838-43, 2010 (corresponding author)
  28. Sanjo N, Katayama T, Hasegawa H, Jin H, Duthie M, Mount H, Mizusawa H, St.George-Hyslop P, Fraser P.
    Localization and trafficking of endogenous anterior pharynx-defective 1, a component of Alzheimer's disease relating γ-secretase.
    Neurosci Let 483(1):53-6, 2010
  29. Hattori T,Shimizu S,Koyama Y, Yamada K, Kuwahara R, Kumamoto N, MatsuzakiS, Katayama T, Ito A, Tohyama M.
    DISC1 regulates cell-cell adhesion, cell-matrix adhesion and neurite outgrowth.
    Mol Psychiat 15(8):778, 798-809, 2010
  30. Okuda H, Kuwahara R, Matsuzaki S, Miyata S, Kumamoto N, Hattori T, Shimizu S, Yamada K, Kawamoto K, Hashimoto R, Takeda M, Katayama T, Tohyama M.
    Dysbindin regulates the transcriptional level of Myristoylated alanine-rich protein kinase C substrate via the interaction with NF-YB in mice brain.
    PLoS ONE 5(1):e8773, 2010
  31. Yamada K, Matsuzaki S, Hattori S, Kuwahara R, Taniguchi M, Hashimoto H, Shintani N, Baba A, Kumamoto N, Yamada K, Yoshikawa T, Katayama T, Tohyama T.
    Increased Stathmin1 Expression in the Dentate Gyrus of Mice Causes Abnormal Axonal Arborizations.
    PLoS ONE 5(1):e8596, 2010 (corresponding author)
  32. Matsuzaki S, Hiratsuka T, Kuwahara R, Katayama T, Tohyama M.
    Caspase-4 is partially cleaved by calpain via the impairment of Ca2+ homeostasis under the ER stress.
    Neurochem Int, 56(2):352-356, 2009
  33. Kobayashi S, Sasaki T, Katayama T, Nagano A, Sato K.
    Temporal-spatial expression of presenilin1 and the production of amyloid-β after acute spinal cord injury in adult rat.
    Neurochem Int, 56(3):387-93, 2010 (corresponding author)
  34. Manabe T, Katayama T, Tohyama M.
    HMGA1a Recognition Candidate DNA Sequences in Humans
    PLoS ONE, 4(11), e8004, 2009
  35. Anitha A, Nakamura K, Yamada K, Iwayama Y, Toyota T, Takei N, Iwata Y, Suzuki S, Sekine Y, Matsuzaki H, Kawai M, Thanseem i, Miyoshi K, Katayama T, Matsuzaki S, Baba K, Honda A, Hattori T, Shimizu S, Kumamoto N, Kikuchi M, Tohyama M, Yoshikawa T, Mori N.
    Association studies and gene expression analyses of the DISC1-interacting molecules, pericentrin 2 (PCNT2) and DISC1-binding zinc finger protein (DBZ), with schizophrenia and with bipolar disorder
    Am J Med Gen (Neuropsychiatric Genetics), 150B(7):967-76, 2009
  36. Kubota K, Kumamoto N, Matsuzaki S, Hashimoto R, Hattori T, Okuda H, Takamura H, Takeda M, Katayama T, Tohyama M.
    Dysbindin engages in c-Jun N-terminal kinase activity and cytoskeletal organization
    Biochem Biophys Res Commun, 379(2):191-5, 2009
  37. Shimizu S, Matsuzaki S, Hattori T, Kumamoto N, Miyoshi K, Katayama T, Tohyama M.
    DISC1 regulates centrosomal microtuble network formation by the interaction with Kendrin
    Biochem Biophys Res Commun,  377(4):1051-6, 2008
  38. Koyama Y, Matsuzaki S, Gomi F, Yamada K, Katayama T, Sato K, Kumada T, Fukuda A, Matsuda S, Tano Y, Tohyama M.
    Induction of Amyloid-β Accumulation by ER Calcium Disruption and Resultant Upregulation of Angiogenic Factors in ARPE19 Cells
    Invest Ophthalmol Vis Sci., 49(6):2376-83, 2008
  39. Yukioka F, Matsuzaki S, Kawamoto K, Koyama Y, Hitomi J, Katayama T, Tohyama M.
    Presenilin-1 mutation activates the signaling pathway of caspase-4 in endoplasmic reticulum stress-induced apoptosis
    Neurochem Int, 52(4-5):683-7, 2008
  40. Tamura N, Ohno K, Katayama T, Kanayama N, Sato K.
    The PDZ-LIM protein CLP36 is required for actin stress fiber formation and focal adhesion assembly in BeWo cells
    Biochem Biophys Res Commun, 364(3):589-94, 2007
  41. Yamagishi S*, Koyama Y*, Katayama T*, Taniguchi M, Hitomi J, Kato M, Aoki M, Itoyama Y, Kato S, Tohyama M. (* equal contribution)
    An in vitro model for Lewy Body-like Hyaline Inclusion/Astrocytic Hyaline Inclusion: Induction by ER stress with an ALS-linked SOD1 Mutation
    PLoS ONE, 2007 Oct 10;2(10):e1030.
  42. Anitha A, Nakamura A, Yamada K, Iwayama Y, Toyota T, Takei N, Iwata Y, Suzuki K, Sekine Y, Matsuzaki H, Kawai M, Miyoshi K, Katayama T, Matsuzaki S, Baba K, Honda A, Hattori T, Shimizu S, Kumamoto N, Tohyama M, Yoshikawa T, Mori N.
    Gene and expression analyses reveal enhanced expression of pericentrin 2 (PCNT2) in bipolar disorder
    Biological Psychiatry, 63(7):678-85, 2008
  43. Manabe T, Ohe K, Katayama T, Matsuzaki S, Yanagita T,Okuda H, Bando Y, Imaizumi K, Reeves R, Tohyama M, Mayeda A.
    HMGA1a: Sequence-specific RNA-binding factor causing sporadic Alzheimer’s disease-linked exon skipping of Presenilin-2 pre-mRNA
    Genes to Cells, 12(10):1179-91, 2007
  44. Matsuzaki S, Yasuda Y, Kobayashi S, Koyama Y, Kawamoto K, Katayama T, Tohyama M.
    Monomeric Aβ and metals reduce their cytotoxicities to each other.
    Biochem Biophys Res Commun, 358(2):540-544, 2007
  45. Hattori T, Baba K, Matsuzaki S, Honda A, Miyoshi K, Inoue K, Taniguchi M, Hashimoto H, Shintani N, Baba A, Shimizu S, Yukioka F, Kumamoto N, Yamaguchi A, Tohyama M, Katayama T.
    A novel DISC1-interacting partner DBZ (DISC1-Binding Zinc finger protein): implication in the modulation of DISC1-dependent nurite outgrowth.
    Molecular Psychiatry, 12(4):398-407, 2007
  46. Rogaeva E, Meng Y, Lee JH, Gu Y, Kawarai T, Zou F, Katayama T, Baldwin CT, Cheng R, Hasegawa H, Chen F, Shibata N, Lunetta KL, Pardossi-Piquard R, Bohm C, Wakutani Y, Cupples LA, Cuenco KT, Green RC, Pinessi L, Rainero I, Sorbi S, Bruni A, Duara R, Friedland RP, Inzelberg R, Hampe W, Bujo H, Song YQ, Andersen OM, Willnow TE, Graff-Radford N, Petersen RC, Dickson D, Der SD, Fraser PE, Schmitt-Ulms G, Younkin S, Mayeux R, Farrer LA, St George-Hyslop P.
    The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease.
    Nature Genetics, 39(2):168-77, 2007
  47. Nakahara S, Saito T, Kndo N, Moriwaki K, Noda K, Ihara S, Takahashi M, Ide Y, Gu J, Inohara H, Katayama T, Tohyama M, Kubo T, Taniguchi N, Miyoshi E.
    A secreted type of β1,6 N-acetylglucosaminiyltransferase V (GnT-V), a novel angiogenesis inducer is regulated by γ-secretase.
    FASEB J. 20(14):2451-9. 2006
  48. Okuda H., Manabe T., Yanagita T., Matsuzaki S., Bando Y., Katayama T., Wanaka A. and Tohyama M.
    Novel interaction between HMGA1a and StIP1 in murine terminally differentiated retina.
    Mol. Cell Neurosci. 2006, 33(1):81-7.
  49. Kumamoto N, Matsuzaki S, Inoue K, Hattori T, Shimizu S, Hashimoto R, Yamatodani A, Katayama T, Tohyama M.
    Hyperactivation of midbrain dopaminergic system in schizophrenia could be attributed to the down-regulation of dysbindin.
    Biochem Biophys Res Commun. 2006, 345(2):904-9.
  50. Chen F, Hasegawa H, Schmitt-Ulms G, Kawarai T, Bohm C, Katayama T, Gu Y, Sanjo N, Glista M, Rogaeva E, Wakutani Y, Pardossi-Piquard R, Ruan X, Tandon A, Checler F, Marambaud F, Hansen K, Westaway D, St George-Hyslop P, Fraser P.
    TMP21 Is A Presenilin Complex Component That Modulatesγ- But Not ε-Secretase Activity.
    Nature 2006, 440(7088):1208-12
  51. Matsuda S, Gomi F, Katayama T, Koyama Y, Yasuo Tano Y and Tohyama M.
    Induction of Connective Tissue Growth Factor in Retinal Pigment Epithelium Cells by Oxidative Stress.
    J J Ophta. 2006, 50(3):229-34.
  52. Miyata S, Mori Y, Fujiwara T, Ikenaka K, Matsuzaki S, Oono K, Katayama T, Tohyama M.
    Local protein synthesis by BDNF is potentiated in hippocampal neurons exposed to ephrins.
    Brain Res Mol Brain Res. 2005, 134(2):333-7.
  53. Yanagita T, Manabe T, Okuda H, Matsuzaki S, Bando Y, Katayama T, Tohyama M.
    Possible involvement of the expression and phosphorylation of N-Myc in the induction of HMGA1a by hypoxia in the human neuroblastoma cell line.
    Neurosci. Let. 2005. 374(1):47-52.
  54. Yamada K, Nakamura K, Minabe Y, Iwayama-Shigeno Y, Takao H, Toyota T, Hattori E, Takei N, Sekine Y, Suzuki K, Iwata Y, Miyoshi K, Honda A, Baba K, Katayama T, Tohyama M, Mori N, Yoshikawa T. 
    Association analysis of FEZ1 variants with schizophrenia in Japanese cohorts.
    Biol Psychiatry. 2004, 56(9):683-90.
  55. Hasegawa H, Sanjo N, Chen F, Gu YJ, Shier C, Petit A, Kawarai T, Katayama T, Schmidt SD, Mathews PM, Schmitt-Ulms G, Fraser PE, St George-Hyslop P.
    Both the sequence and length of the C terminus of PEN-2 are critical for intermolecular interactions and function of presenilin complexes.
    J Biol Chem. 2004, 279(45):46455-63.
  56. Bando Y, Katayama T, Taniguchi M, Ishibashi T, Tsukamoto Y, Matsuo N, Ogawa S, Tohyama M.
    RA410 suppresses MPP+ and 6-hydroxydopamine induced cell death in SH-SY5Y cells.
    Neurobiol Dis 2005, 18(1):143-51.
  57. Bando Y, Onuki R, Katayama T, Manabe T, Taira K, Tohyama M.
    Double-strand RNA dependent protein kinase (PKR) is involved in the extrastriatal degeneration in Parkinson’s disease and Huntington’s disease.
    Neurochem Int 2005, 46(1):11-8.
  58. Hori O, Ichinoda F, Yamaguchi A, Tamatani T, Taniguchi M, Koyama Y, Katayama T, Tohyama M, Stern DM, Ozawa K, Kitao Y, Ogawa S.
    Role of Herp in the endoplasmic reticulum stress response.
    Genes Cells 2004, 9(5):457-469.
  59. Bando Y, Tsukamoto Y, Katayama T, Ozawa K, Kitao Y, Hori O, Stern DM, Yamauchi A, Ogawa S.
    ORP150/HSP12A protects renal tubular epithelium from ischemia-induced cell death.
    FASEB J 2004, 18(12):1401-3
  60. Nishikawa A, Manabe T, Katayama T, Kudo T, Matsuzaki S, Yanagita T, Okuda H, Bando Y, Tohyama M.
    Novel function of PS2V: change in conformation of tau proteins.
    Biochem Bioph Res Co 2004, 318(2):435-438.
  61. Miyoshi K, Asanuma M, Miyazaki I, Diaz-Corrales F.J, Katayama T, Tohyama M, Ogawa N.
    DISC1 localizes to the centrosome by binding to kendrin.
    Biochem Bioph Res Co 2004, 317(4):1195-1199.
  62. Hitomi J, Katayama T, Eguchi Y, Kudo T, Taniguchi M, Koyama Y, Manabe T, Yamagishi S, Bando Y, Imaizumi K, Tsujimoto Y, Tohyama M.
    Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death.
    J Cell Biol 2004, 165(3): 347-356. (co-corresponding author)
  63. Bando Y, Katayama T, Aleshin AT, Manabe T, Tohyama M.
    GRP94 reduces cell death in SH-SY5Y cells perturbed calcium homeostasis.
    Apoptosis 2004, 9: 501-508.
  64. Oono K, Yoneda T, Miyata S, Manabe T, Yamagishi S, Matsuda S, Hitomi J, Imaizumi K, Katayama T, Tohyama M.
    JAB1 participates in unfolded protein responses by association and dissociation with IRE1.
    Neurochem Int 2004, 45(5): 765-772. (corresponding author)
  65. Hitomi J, Katayama T, Taniguchi M, Honda A, Imaizumi K, Tohyama M.
    Apoptosis induced by endoplasmic reticulum stress depends on activation of caspase-3 via caspase-12.
    Neurosci Let 2004, 357(2):127-130. (corresponding author)
  66. Onuki R, Bando Y, Suyama E, Katayama T, Kawasaki H, Sugiyama Y, Baba T, Tohyama M, Taira K.
    An RNA-dependent protein kinase is involved in tunicamycin-induced apoptosis and Alzheimer’s disease
    EMBO J 2004, 25;23(4):959-968
  67. Matsuzaki S, Manabe T, Katayama T, Nishikawa A, Yanagita T, Okuda H, Yasuda Y, Miyata S, Meshitsuka S, Tohyama M.
    Metals accelerate production of the aberrant splicing isoform of the Presenilin-2
    J Neurochem 2004, 88(6), 1345 -1351. (corresponding author)
  68. Honda A, Miyoshi K, Baba K, Taniguchi M, Koyama Y, Kuroda S, Katayama T, Tohyama M.
    Expression of fasciculation and elongation protein zeta-1 (FEZ1) in the developing rat brain.
    Brain Res Mol Brain Res 2004, 122(1): 89-92 (corresponding author)
  69. Bando Y, Katayama T, Tamatani M, Kasai K, Taniguchi M, and Tohyama M.
    GRP94 (94kDa Glucose-Regulated Protein) protects from ischemic neuronal cell death against ischemia/reperfusion injury.
    Eur. J. Neurosci. 2003, 18: 1-13
  70. Miyoshi K, Honda A, Baba K, Taniguchi M, Oono K, Fujita T, Kuroda S, Katayama T, Tohyama M.
    Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth.
    Mol Psychiatr 2003, 8(7): 685-694 (corresponding author)
  71. Katayama T, Imaizumi K, Yoneda T, Taniguchi M, Honda A, Manabe T, Hitomi J, Oono K, Baba K, Miyata S, Matsuzaki S, Takatsuji K, Tohyama M.
    Role of ARF4L in Recycling between Endosomes and the Plasma Membrane.
    Cell Mol Neurobiol 2004, 24(1):137-147 (corresponding author)
  72. Manabe T, Katayama T, Imaizumi K, Sato N, Gomi F, Hitomi H, Yanagita T, Kudo T, Honda A, Mori Y, Matsuzaki S, Mayeda A, Tohyama M.
    Induced HMGA1a expression causes aberrant splicing of Presenilin-2 pre-mRNA in sporadic Alzheimer’s disease.
    Cell Death Diff 2003, 10: 698-708 (corresponding author)
  73. Yasuda Y, Katayama T, Imaizumi K, Yatera M, Tohyama M, Kudo T, Takeda M.
    Familial Alzheimer’s Disease linked Presenilin-1 mutants impede translation regulation under endoplasmic reticulum stress.
    Biochem Bioph Res Co 2002 Aug 16;296(2):313-8
  74. Manabe T, Katayama T, Sato N, Kudo T, Matsuzaki S, Imaizumi K, Tohyama M.
    The cytosolic inclusion bodies that consist of splice variants that lack exon 5 of the presenilin-2 gene differ obviously from Hirano bodies observed in the brain from sporadic cases of Alzheimer’s disease patients.
    Neurosci Lett  2002, 328(2):198-200 (corresponding author)
  75. Katayama T, Imaizumi K, Honda A, Yoneda T, Kudo T, Takeda M, Mori K,
    Rozmahel R, Fraser P, St.George-Hyslop P, Tohyama T.
    Disturbed activation of ER stress transducers by FAD-linked PS1 mutations
    J Biol Chem  2001, 276(46): 43446-43454
  76. Imaizumi K, Katayama T, Tohyama M.
    Presenilin and the UPR, Nat. Cell Biol. (Letter) 2001, 3(5): E104
  77. Yui D, Yoneda T, Oono K, Katayama T, Yasuda Y, Imaizumi K, Tohyama M.
    Interchangeable binding of Bcl-10 to TRAF2 and cIAPs regulates apoptosis signaling.
    Oncogene 2001, 20:4317-4323
  78. Yoneda T, Imaizumi K, Oono K, Yui D, Gomi F, Katayama T, Tohyama M.
    Activation of Caspase-12, an Endoplasmic Reticulum (ER) Resident Caspase, through Tumor Necrosis Factor Receptor-associated Factor 2-dependent Mechanism in Response to the ER stress.
    J Biol Chem 2001, 276(17): 13935-13940
  79. Sato N, Imaizumi K, Manabe T, Taniguchi M, Hitomi J, Katayama T, Yoneda T,
    Morihara T, Yasuda Y, Takagi T, Kudo T, Tsuda T, Itoyama Y, Makifuchi T, Fraser PE, St. George-Hyslop P, Tohyama M.
    Increased production of β-amyloid and vulnerability to ER stress by an aberrant spliced form of presenilin-2.
    J Biol Chem 2001, 276(3): 2108-2114
  80. Morihara T, Katayama T, Sato N, Yoneda T, Manabe T, Hitomi J, Abe H,
    Imaizumi K and Tohyama M.
    Absence of endoproteolysis but no effects on amyloid β production by alternative splicing forms of presenilin-1, which lack exon 8 and replace D257A.
    Brain Res Mol Brain Res, 2000, 85(1-2):85-90.
  81. Miyoshi K, Katayama T, Imaizumi K, Taniguchi M, Mori Y, Hitomi J, Yui D,
    Manabe T, Gomi F, Yoneda T & Tohyama M
    Characterization of mouse Ire1α: cloning, mRNA localization in the brain and functional analysis in a neural cell line.
    Brain Res Mol Brain Res, 2000, 85(1-2): 68-76.
  82. Mori Y, Imaizumi K, Katayama T, Yoneda T and Tohyama M
    Two cis-acting elements in the 3' untranslated region of α-CaMKII regulate its dendritic targeting
    Nat Neurosci 2000 ; 3(11):1079-1084
  83. Yoneda T, Imaizumi K, Maeda M, Yui D, Manabe T, Katayama T, Sato N, Gomi F, Morihara T, Mori Y, Miyoshi K, Hitomi J, Ugawa S, Yamada S, Okabe M, Tohyama M.
    Regulatory mechanisms of TRAF2-mediated signal transduction by Bcl10, a MALT lymphoma-associated protein.
    J Biol Chem. 2000 ;275(15):11114-20.
  84. Katayama T, Imaizumi K, Sato N, Miyoshi K, Kudo T, Hitomi J, Morihara T, Yoneda T, Gomi F, Mori Y, Nakano Y, Takeda J, Tsuda T, Itoyama Y, Murayama O, Takashima A, St George-Hyslop P, Takeda M, Tohyama M.
    Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response.
    Nat Cell Biol. 1999 ,1(8):479-485.
  85. Imaizumi K, Morihara T, Mori Y, Katayama T, Tsuda M, Furuyama T, Wanaka A, Takeda M, Tohyama M.
    The cell death-promoting gene DP5, which interacts with the BCL2 family, is induced during neuronal apoptosis following exposure to amyloid beta protein.
    J Biol Chem. 1999 ,274(12):7975-81.
  86. Katayama T, Imaizumi K, Tsuda M, Mori Y, Takagi T, Tohyama M.
    Expression of an ADP-ribosylation factor like gene, ARF4L, is induced after transient forebrain ischemia in the gerbil.
    Brain Res Mol Brain Res. 1998 ,56(1-2):66-75.
  87. Tanimukai H, Imaizumi K, Kudo T, Katayama T, Tsuda M, Takagi T, Tohyama M, Takeda M.
    Alzheimer-associated presenilin-1 gene is induced in gerbil hippocampus after transient ischemia.
    Brain Res Mol Brain Res. 1998,54(2):212-8.
  88. Tsuda M, Imaizumi K, Katayama T, Kitagawa K, Wanaka A, Tohyama M, Takagi T.
    Expression of zinc transporter gene, ZnT-1, is induced after transient forebrain ischemia in the gerbil.
    J Neurosci. 1997,17(17):6678-84.
  89. Kato M, Katayama T, Iwata H, Yamamura M, Matsuoka Y, Narita H.
    In vivo characterization of T-794, a novel reversible inhibitor of monoamine oxidase-A, as an antidepressant with a wide safety margin.
    J Pharmacol Exp Ther. 1998 ,284(3):983-90.
  90. Kato M, Iwata H, Katayama T, Asai H, Narita H, Endo T.
    Possible therapeutic effect of T-794, a novel reversible inhibitor of monoamine oxidase-A, on post-stroke emotional disturbances, assessed in animal models of depression.
    Biol Pharm Bull. 1997,20(4):349-53.
  91. Yamahara J, Kobayashi G, Matsuda H, Katayama T, Fujimura H.
    Vascular dilatory action of Artemisia capillaris bud extracts and their active constituent.
    J Ethnopharmacol. 1989 ,26(2):129-36.
  92. Yamahara J, Kobayashi G, Matsuda H, Katayama T, Fujimura H.
    The effect of scoparone, a coumarin derivative isolated from the Chinese crude drug Artemisiae capillaris flos, on the heart.
    Chem Pharm Bull. 1989,37(5):1297-9.
  93. Yamahara J, Matsuda H, Kobayashi G, Katayama T, Fujimura H.
    Effect of Alismol isolated from Alismatis rhizoma on working heart perfusion in rat
    Phytotherapy Research. 1989, 3(2): 72-74
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